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Recombinant mouse Interleukin-2 receptor subunit beta (Il2rb), partial

CAT: 0399-CSB-YP011650MO-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-YP011650MO-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
High affinity IL-2 receptor subunit betap70-75; CD122
Abbreviation
Recombinant Mouse Il2rb protein, partial
Gene Name
Il2rb
UniProt
P16297
Expression Region
27-240aa
Organism
Mus musculus (Mouse)
Target Sequence
AVKNCSHLECFYNSRANVSCMWSHEEALNVTTCHVHAKSNLRHWNKTCELTLVRQASWACNLILGSFPESQSLTSVDLLDINVVCWEEKGWRRVKTCDFHPFDNLRLVAPHSLQVLHIDTQRCNISWKVSQVSHYIEPYLEFEARRRLLGHSWEDASVLSLKQRQQWLFLEMLIPSTSYEVQVRVKAQRNNTGTWSPWSQPLTFRTRPADPMKE
Tag
N-terminal 6xHis-tagged
Type
In Stock Protein
Source
Yeast
Field of Research
Others
Relevance
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Molecular Weight
27.1 kDa
References & Citations
Murine interleukin 2 receptor beta chain dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion.Kono T., Doi T., Yamada G., Hatakeyama M., Minamoto S., Tsudo M., Miyasaka M., Miyata T., Taniguchi T.Proc. Natl. Acad. Sci. U.S.A. 87:1806-1810 (1990)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial

UniProtKB · P16297

Interleukin-2 receptor subunit beta

IL2RB_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P16297
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Il2rb
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB
EC number
—
Processing
Precursor
Secondary accessions
Q3TZT2
Protein keywords

Technical term

3D-structureReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

Receptor

Domain

SignalTransmembraneTransmembrane helix

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