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Recombinant Mouse Angiogenin-4 (Ang4)

CAT: 0399-CSB-YP661010MO-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-YP661010MO-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Ang4Angiogenin-4; EC 3.1.27.-
Abbreviation
Recombinant Mouse Ang4 protein
Gene Name
Ang4
UniProt
Q3TMQ6
Expression Region
25-144aa
Organism
Mus musculus (Mouse)
Target Sequence
QNERYEKFLRQHYDAKPNGRDDRYCESMMKERKLTSPCKDVNTFIHGTKKNIRAICGKKGSPYGENFRISNSPFQITTCTHSGASPRPPCGYRAFKDFRYIVIACEDGWPVHFDESFISP
Tag
N-terminal 6xHis-SUMO-tagged
Type
In Stock Protein
Source
Yeast
Field of Research
Cardiovascular
Relevance
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro) . Has low ribonuclease activity (in vitro) . Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro) . Has low ribonuclease activity (in vitro) . Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro) .
Molecular Weight
29.9 kDa
References & Citations
"Angiogenins: a new class of microbicidal proteins involved in innate immunity."Hooper L.V., Stappenbeck T.S., Hong C.V., Gordon J.I.Nat. Immunol. 4:269-273 (2003)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Full Length of Mature Protein

UniProtKB · Q3TMQ6

Angiogenin-4

ANG4_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q3TMQ6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Ang4
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.1.27.-
Processing
Precursor
Secondary accessions
Q3UWE7, Q80XS4, Q80Z85
Protein keywords

Technical term

3D-structureReference proteome

Biological process

Angiogenesis

Molecular function

AntibioticAntimicrobialEndonucleaseHydrolaseNuclease

Cellular component

Cytoplasmic vesicleNucleusSecreted

PTM

Disulfide bond

Domain

Signal

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