Recombinant Human Integrin alpha-V (ITGAV), partial

CAT: 0399-CSB-YP011877HU-01Size: 20 µgDry Ice: NoHazardous: No
CAT#:0399-CSB-YP011877HU-01Size:20 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Product Name Alternative
Vitronectin receptor subunit alpha; CD51
Abbreviation
Recombinant Human ITGAV protein, partial
Gene Name
ITGAV
UniProt
P06756
Expression Region
891-1048aa
Organism
Homo sapiens (Human)
Target Sequence
DLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
Tag
N-terminal 6xHis-tagged
Type
Developed Protein
Source
Yeast
Field of Research
Cardiovascular
Relevance
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with Extracellular domain viral Tat protein ses to enhance angiogenesis in Kaposi's sarcoma lesions.
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV
Molecular Weight
19.7 kDa
References & Citations
Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.Suzuki S., Argraves W.S., Arai H., Languino L.R., Pierschbacher M.D., Ruoslahti E.J. Biol. Chem. 262:14080-14085 (1987)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial

Related Products

CatalogName
CSB-MP011877HU-01Recombinant Human Integrin alpha-V&Integrin beta-6 (ITGAV&ITGB6) Heterodimer Protein
CSB-MP011877MO-01Recombinant Mouse Integrin alpha-V&Integrin beta-6 (Itgav&Itgb6) Heterodimer Protein
CSB-YP011875HU-01Recombinant Human Integrin alpha-L (ITGAL), partial
CSB-EP011875HU-01Recombinant Human Integrin alpha-L (ITGAL), partial
CSB-MP011875HU-01Recombinant Human Integrin alpha-L (ITGAL), partial
CSB-EP011876HUc7-01Recombinant Human Integrin alpha-M (ITGAM), partial
CSB-EP011867HU1-01Recombinant Human Integrin alpha-4 (ITGA4), partial
CSB-EP011864HU-01Recombinant Human Integrin alpha-2 (ITGA2), partial
CSB-EP011864HUb0-01Recombinant Human Integrin alpha-2 (ITGA2), partial
CSB-YP011864HU-01Recombinant Human Integrin alpha-2 (ITGA2), partial

Alternative Products

CatalogName
216745ITGAV (Integrin alpha V)
483760ITGAV (Integrin Alpha-V, Integrin Subunit Alpha V)
AP72630-01Recombinant Human Integrin alpha-V(ITGAV), partial
MBS1033344-01Recombinant Human Integrin alpha-V (ITGAV), partial
MBS964935Recombinant Bovine Integrin alpha-V (ITGAV) , partial
MBS956068Recombinant Chicken Integrin alpha-V (ITGAV), partial
MBS955624-01Recombinant Mouse Integrin alpha-V (Itgav) , partial
abx404741-01Integrin Alpha V (ITGaV) Antibody
MBS2029529-01Recombinant Integrin Alpha V (ITGaV)
abx402214-01Integrin alpha-V (ITGAV) Antibody

Popular Products