Products for Research Use Only
RegisterLogin

Recombinant Human Diphthamide biosynthesis protein 2 (DPH2)

CAT: 0399-CSB-EP859031HU-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0399-CSB-EP859031HU-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Product Name Alternative
DPH2 homolog ; HsDph2Diphthamide biosynthesis protein 2 homolog-like 2 ; DPH2-like 2
Abbreviation
Recombinant Human DPH2 protein
Gene Name
DPH2
UniProt
Q9BQC3
Expression Region
1-489aa
Organism
Homo sapiens (Human)
Target Sequence
MESMFSSPAEAALQRETGVPGLLTPLPDLDGVYELERVAGFVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFILGDTAYGSCCVDVLGAEQAGAQALIHFGPACLSPPARPLPVAFVLRQRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHALEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLERFGRRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLGWAPGQPFSSCCPDTGKTQDEGARAGRLRARRRYLVERARDARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILAPCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVALPPPESELWETPDVSLITGDLRPPPAWKSSNDHGSLALTPRPQLELAESSPAASFLSSRSWQGLEPRLGQTPVTEAVSGRRGIAIAYEDEGSG
Tag
N-terminal 6xHis-SUMO-tagged
Type
Developed Protein
Source
E.coli
Field of Research
Cell Biology
Relevance
Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) .
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) .
Molecular Weight
68.1 kDa
References & Citations
Cloning and localization of a human diphthamide biosynthesis-like protein-2 gene, DPH2L2.Schultz D.C., Balasara B.R., Testa J.R., Godwin A.K.Genomics 52:186-191 (1998)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Full Length

UniProtKB · Q9BQC3

2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

DPH2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BQC3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DPH2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8MVC9, B2RDE3, B4DNI8, O60623
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Disease

Disease variantDwarfismEctodermal dysplasiaHypotrichosisIntellectual disability

Ligand

IronIron-sulfurMetal-binding

Technical term

Proteomics identificationReference proteome

Related Products

CatalogName
CSB-CL859031HUDPH2
CSB-PA859031LA01HU-01DPH2 Antibody
CSB-PA007130GA01HUDPH2 Antibody
CSB-PA859031LC01HU-01DPH2 Antibody, FITC conjugated
CSB-PA859031LB01HU-01DPH2 Antibody, HRP conjugated
CSB-PA859031LD01HU-01DPH2 Antibody, Biotin conjugated
CSB-EP6008GYB-01Recombinant Verticillium dahliae Pigment biosynthesis protein Ayg1
CSB-EP002299HU-01Recombinant Human Bifunctional purine biosynthesis protein ATIC (ATIC)
CSB-EP002299CH-01Recombinant Chicken Bifunctional purine biosynthesis protein ATIC (ATIC), partial
CSB-EP708633BAAB(A4)-01Recombinant Bacteroides fragilis Biotin biosynthesis bifunctional protein BioAB (bioB)

Alternative Products

CatalogName
abx232516Diphthamide Biosynthesis Protein 2 (DPH2) Antibody
MBS6002710-01DPH2, NT (DPH2, DPH2L2, Diphthamide biosynthesis protein 2, DPH2 homolog, Diphthamide biosynthesis protein 2 homolog-like 2)
MBS6293336-01DPH2, NT (DPH2, DPH2L2, Diphthamide biosynthesis protein 2, DPH2 homolog, Diphthamide biosynthesis protein 2 homolog-like 2) (Biotin)
MBS6293335-01DPH2, NT (DPH2, DPH2L2, Diphthamide biosynthesis protein 2, DPH2 homolog, Diphthamide biosynthesis protein 2 homolog-like 2) (APC)
479621DPH2 (Diphthamide Biosynthesis Protein 2, DPH2 Homolog (S. Cerevisiae) )
abx680238-01Human Diphthamide Biosynthesis Protein 2 (DPH2) Protein
MBS6293344-01DPH2, NT (DPH2, DPH2L2, Diphthamide biosynthesis protein 2, DPH2 homolog, Diphthamide biosynthesis protein 2 homolog-like 2) (PE)
MBS6293337-01DPH2, NT (DPH2, DPH2L2, Diphthamide biosynthesis protein 2, DPH2 homolog, Diphthamide biosynthesis protein 2 homolog-like 2) (FITC)
MBS6293334-01DPH2, NT (DPH2, DPH2L2, Diphthamide biosynthesis protein 2, DPH2 homolog, Diphthamide biosynthesis protein 2 homolog-like 2) (AP)
GTR19027456-01Recombinant Human Diphthamide biosynthesis protein 2 (DPH2)

Popular Products