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Recombinant Sheep Interferon gamma (IFNG)

CAT: 0399-CSB-EP011050SH-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-EP011050SH-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
IFNG; Interferon gamma; IFN-gamma
Abbreviation
Recombinant Sheep IFNG protein
Gene Name
IFNG
UniProt
P17773
Expression Region
24-166aa
Organism
Ovis aries (Sheep)
Target Sequence
QGPFFKEIENLKEYFNASNPDVAKGGPLFSEILKNWKEESDKKIIQSQIVSFYFKLFENLKDNQVIQRSMDIIKQDMFQKFLNGSSEKLEDFKRLIQIPVDDLQIQRKAINELIKVMNDLSPKSNLRKRKRSQNLFRGRRASM
Tag
N-terminal 6xHis-tagged
Type
In Stock Protein
Source
E.coli
Field of Research
Others
Relevance
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Molecular Weight
20.9 kDa
References & Citations
The molecular cloning of the ovine gamma-interferon cDNA using the polymerase chain reaction.McInnes C.J., Logan M., Redmond J., Entrican G., Baird G.D.Nucleic Acids Res. 18:4012-4012 (1990)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Full Length of Mature Protein

UniProtKB · P17773

Interferon gamma

IFNG_SHEEP · Ovis aries

View on UniProt ↗
Primary accession
P17773
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNG
Protein existence
2: Evidence at transcript level
Organism
Ovis aries (Sheep)
Taxonomy ID
9940
Alternative names
IFN-gamma
EC number
—
Processing
Precursor
Secondary accessions
Q204I9
Protein keywords

Biological process

Antiviral defenseGrowth regulation

Molecular function

Cytokine

PTM

GlycoproteinPyrrolidone carboxylic acid

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal

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