Products for Research Use Only
RegisterLogin

Phenserine

CAT: 0804-HY-103374-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-103374-01Size:10 mM - 1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Phenserine ((-) -Eseroline phenylcarbamate) is a derivative of Physostigmine and is a potent, noncompetitive, long-acting and selective AChE inhibitor. Phenserine reduces β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ) formation. Phenserine improves cognitive performance and attenuates the progression of Alzheimer's disease[1][2][3].
CAS Number
101246-66-6
Product Name Alternative
(-) -Eseroline phenylcarbamate; (-) -Phenserine
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Amyloid-β; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phenserine.html
Purity
99.55
Solubility
DMSO : 200 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1[C@](N(C)CC2)([H])[C@]2(C)C3=C1C=CC(OC(NC4=CC=CC=C4)=O)=C3
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
Precautions
H315, H319, H335
References & Citations
[1]Klein J. Phenserine. Expert Opin Investig Drugs. 2007 Jul;16 (7) :1087-97.|[2]Asuni AA, et al. Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model. Ann Neurol. 2014 May;75 (5) :684-99.|[3]Janas AM, et al. The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats. Life Sci. 2005 Jan 21;76 (10) :1073-81.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
AChE

Related Products

CatalogName
HY-W043333-01β-keto Phentermine (hydrochloride)
HY-W142083-01DL-3-Phenylserine hydrate

Alternative Products

CatalogName
B7235-50Phenserine
MBS3845428-01(+)-Phenserine
462405-01Phenserine-d5
A20993-10(+) -Phenserine 10mg
A20993-1(+) -Phenserine 1mg
A20993-100(+) -Phenserine 100mg
A20993-50(+) -Phenserine 50mg

Popular Products