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Adam17 Rabbit Polyclonal Antibody (Cy3)

CAT: 0013-GTR18543421Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18543421Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-Adam17 Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.
Product Name Alternative
Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; 3.4.24.86; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; CD156b; ADAM17; CSVP, TACE
UniProt
Q9Z0F8
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived mouse Adam17 recombinant protein (Position: R215-M449) .
Target
Disintegrin and metalloproteinase domain-containing protein 17
Clonality
Polyclonal
Conjugation
Cy3
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Purification
Immunogen affinity purified.
Dilution
Optimal dilutions should be determined by end users.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Notes
For research use only.
Applications Notes
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · Q9Z0F8

Disintegrin and metalloproteinase domain-containing protein 17

ADA17_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9Z0F8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Adam17
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
ADAM 17
EC number
3.4.24.86
Processing
Precursor
Secondary accessions
O88726, Q505A7, Q9R1U4, Q9Z0K3
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinUbl conjugationZymogen

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Biological process

Notch signaling pathway

Technical term

Reference proteome

Domain

SH3-bindingSignalTransmembraneTransmembrane helix

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