Mal-C2-NHS ester

• Description:

  Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mal-c2-nhs-ester.html

• Purity:

  99.30

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(ON1C(CCC1=O)=O)CCCCN2C(C=CC2=O)=O

• Molecular Formula:

  C13H14N2O6

• Molecular Weight:

  294.26

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Andrew Wood, et al. Processes for the synthesis and purification of heterobifunctional cross-linkers. WO2011023680A2.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Non-cleavable Linker

• CAS Number:

  [103750-03-4]