ZWINT Antibody

• Catalog number
  bs-7852R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ZWINT Primary Polyclonal Antibody
• Also known as
  ZWINT PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ZWINT
• Specificity
  This is a highly specific antibody against ZWINT.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZWINT
• Gene ID number
  11130
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HZwint1; KNTC 2 AP; KNTC2AP; MGC 117174; MGC117174; ZW10 interacting protein 1; ZW10 interactor; ZWINT 1; ZWINT1; ZWINT-1; ZWINT_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ZWINT  
• Gene symbol
  ZWINT
• Short name
  Anti-ZWINT
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ZWINT Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13195
• Gene
  ZWINT
• Long gene name
  ZW10 interacting kinetochore protein
• Synonyms gene name
  • ZW10 interactor
• Synonyms
  • KNTC2AP
  • SIP30
  • Zwint1
• Synonyms name
  • SNAP25 interacting protein of 30 kDa
• GenBank acession
  • AF067656
• Locus
  10q21.1
• Discovery year
  2001-06-22
• Pubmed identfication
  • 10806105
• Classification
  • KNL1 complex
• VEGA ID
  OTTHUMG00000018261

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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