PP2A alpha + beta Antibody, Cy5 Conjugated
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Catalog numberbs-0029R-Cy5
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Price:
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Size0.1ml
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Long namePP2A alpha + beta Polyclonal Antibody, Cy5 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy5
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenPP2A alpha + beta
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SpecificityThis is a highly specific antibody against PP2A alpha + beta.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen_range267-309/309
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Subcellular locationCytoplasm, Nucleus
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SourceKLH conjugated synthetic peptide derived from human PP-2A
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Gene ID number5515
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Swiss ProtP67775
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundPP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission625,650nm/670nm
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SynonymsRP-C; PP2Ac; PP2CA; PP2Calpha; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; PPP2CA
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DescriptionThe Anti-PP2A alpha + beta is a α- or alpha protein sometimes glycoprotein present in blood.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugationCy5.5
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French translationanticorps
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Gene target
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Gene symbolPPP2R1B, PPP2R1A
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Short nameAnti-PP2A alpha + beta
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy5
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Alternative nameAnti-PP2A alpha + beta PAb Cy5
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameprotein phosphatase 2 scaffold subunit Abeta
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Synonyms gene name
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
- protein phosphatase 2 regulatory subunit A, beta
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-01-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- STRIPAK complex
- Protein phosphatase 2 scaffold subunits
- Armadillo like helical domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein phosphatase 2 scaffold subunit Aalpha
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Synonyms gene name
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-01-25
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Entrez gene record
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RefSeq identity
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Classification
- STRIPAK complex
- Protein phosphatase 2 scaffold subunits
- Armadillo like helical domain containing
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data