ZAP70 (Tyr292) Antibody
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Catalog numberbs-13548R
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PricePlease ask
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Size0.1ml
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Long nameZAP70 (Tyr292) Primary Polyclonal Antibody
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Also known asZAP70 (Tyr292) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenZAP70 Tyr292
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SpecificityThis is a highly specific antibody against ZAP70 Tyr292.
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Modification sPhosphorylation
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Modification site sTyr292
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human Zap-70 around the phosphorylation site of Tyr292
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Gene ID number7535
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesZAP70 phospho Y292; ZAP70 phospho Tyr292; p-Zap-70Tyr292; p-Zap-70Y292; p-ZAP70 Y292; p-ZAP70 Tyr292; ZAP-70; ZAP 70; ZAP70; zeta-associated protein 70; ZAP-70=protein tyrosine kinase Syk homolog {SH2-like and C-terminal kinase domains}; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-associated protein; Syk-related tyrosine kinase. SRK; STD; TZK; ZAP70_HUMAN; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolZAP70
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Short nameAnti-ZAP70 Tyr292
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameZAP70 (Tyr292) Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetzeta-chain (TCR) associated protein kinase 70kDa, SRK and STCD and STD and TZK and ZAP-70, ZAP70 and IDBG-62509 and ENSG00000115085 and 7535, transferase activity, Cell surfaces, Zap70 and IDBG-145089 and ENSMUSG00000026117 and 22637, ZAP70 and IDBG-629842 and ENSBTAG00000005892 and 504509
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Gene info
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Identity
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Gene
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Long gene namezeta chain of T cell receptor associated protein kinase 70
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Synonyms gene
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Synonyms gene name
- SRK
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-05-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
- Syk family tyrosine kinases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data