ZAK/HCCS4 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-13546R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  ZAK/HCCS4 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-ZAK/HCCS4 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ZAK/HCCS4
• Specificity
  This is a highly specific antibody against ZAK/HCCS4.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZAK/HCCS4
• Gene ID Number
  51776
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  AZK; Cervical cancer suppressor gene 4 protein; HCCS 4; HCCS-4; HCCS4; Human cervical cancer suppressor gene 4 protein; Leucine zipper and sterile alpha mot containing kinase; Leucine zipper- and sterile alpha mot-containing kinase; Mitogen activated protein kinase kinase kinase MLT; Mitogen-activated protein kinase kinase kinase MLT; Mixed lineage kinase 7; Mixed lineage kinase related kinase; Mixed lineage kinase related kinase MRK beta; Mixed lineage kinase with a leucine zipper and a sterile alpha mot; Mixed lineage kinase-related kinase; MLK 7; MLK like mitogen activated protein triple kinase; MLK related kinase; MLK-like mitogen-activated protein triple kinase; MLK-related kinase; MLK7; Mlklak; MLT; MLTK; MLTK_HUMAN; MRK; Sterile alpha mot and leucine zipper containing kinase AZK; Sterile alpha mot- and leucine zipper-containing kinase AZK; ZAK.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-ZAK/HCCS4 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  ZAK/HCCS4  
• Gene symbol
  MAP3K20
• Short name
  Anti-ZAK/HCCS4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  ZAK/HCCS4 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  Mitogen-activated protein kinase kinase kinase MLT, ZAK and IDBG-75233 and ENSG00000091436 and 51776, transferase activity, nuclei, B230120H23Rik and IDBG-179557 and ENSMUSG00000004085 and 65964, BT.55601 and IDBG-640550 and ENSBTAG00000001083 and 519251

Gene info

• Identity
  HGNC:17797
• Gene
  MAP3K20
• Long gene name
  mitogen-activated protein kinase kinase kinase 20
• Synonyms
  • MLTKalpha
  • MLTKbeta
  • ZAK
  • MLTK
  • MLK7
  • MRK
• Synonyms name
  • ZAK1 homolog, leucine zipper and sterile-alpha motif kinase (Dictyostelium)
  • mixed lineage kinase 7
• GenBank acession
  • AB049733
• Locus
  2q31.1
• Discovery year
  2016-10-19
• Entrez gene record
  51776
• Pubmed identfication
  • 10924358
• RefSeq identity
  • NM_016653
• Classification
  • Mitogen-activated protein kinase kinase kinases
• VEGA ID
  OTTHUMG00000132297

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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