XL019 for cell activation

XL019 for cell activation is available 2 times from Biovision labs

2609-25 | XL019 for cell activationsize: 25 mg | 530.73 USD

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2609-5 | XL019 for cell activationsize: 5 mg | 177.3 USD

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  • Description
    XL019 is a potent, highly selective and reversible JAK2 inhibitor (IC₅₀ = 2.2 nM). Inhibits JAK1 (IC₅₀ = 134.3 nM), JAK3 (IC50 = 214.2 nM) and TYK2 (IC₅₀ = 348.3 nM) at higher concentrations. XL019 displays significant dose-dependent pharmacodynamic and antitumor effect in a mouse xenograft model.
  • Peptide sequence
    N/A
  • CAS number
    945755-56-6
  • Molecular weight
    444.53
  • Category
    Biochemicals
  • Other name
    (S)-N-(4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)phenyl)pyrrolidine-2-carboxamide  
  • Molecular formula
    C₂₅H₂₈N₆O₂
  • Physical appearance
    Light yellow to light brown solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    >98% by HPLC
  • Reconstitute instructions
    DMSO (~ 15 mg/ml)
  • Storage condition
    -20 ̊C
  • Shipping condition
    Gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    XL019 for activation
  • Technique
    activation
  • Alternative name
    XL019 to measure cellular activation
  • Tissue
    cell
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