Tyrosinase Antibody

• Catalog number
  bs-0819R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Tyrosinase Primary Polyclonal Antibody
• Also known as
  Tyrosinase PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Tyrosinase
• Specificity
  This is a highly specific antibody against Tyrosinase.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Lumenal
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tyrosinase
• Gene ID number
  7299
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Tyrosinase is the key enzyme for melanin,synthesis in mammalian melanocytes and has been considered to be a unique marker for the study of melanocyte differentiation. A cDNA library was constructed from poly(A)+ mRNA from mouse melanocytes and screened using anti- tyrosinase antiserum and oligonucleotide probes corresponding to amino acid sequence of tyrosinase. sequencing of some cDNA clones positive in these screenings gave a nucleotide sequence of 1838 nucleotides including a open reading frame of 1344 nucleotides that was found to correspond exactly to the amino acid sequence of the cyanogen bromide fragments of tyrosinase.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  LB24 AB; LB24-AB; Monophenol monooxygenase; SK29 AB; Tumor rejection antigen AB; LB24 AB; Monophenol monooxygenase; OCA1A; OCAIA; Oculocutaneous albinism IA; SK29 AB; SK29-AB; Tumor rejection antigen AB; TYR; tyrosinase oculocutaneous albinism IA; TYRO_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Tyrosinase  
• Gene symbol
  TYRL, TYR, TYRP1
• Short name
  Anti-Tyrosinase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Tyrosinase Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12443
• Gene
  TYRL
• Long gene name
  tyrosinase like (pseudogene)
• Synonyms gene name
  • tyrosinase-like
• GenBank acession
  • M63240
• Locus
  11p11.12
• Discovery year
  1988-08-16
• Entrez gene record
  7300
• Pubmed identfication
  • 1903356
  • 8234203
  • 17355913
• VEGA ID
  OTTHUMG00000166674

Gene info

• Identity
  HGNC:12442
• Gene
  TYR
• Long gene name
  tyrosinase
• Synonyms
  • OCAIA
  • OCA1A
  • OCA1
• Synonyms name
  • oculocutaneous albinism IA
• GenBank acession
  • M27160
• Locus
  11q14.3
• Discovery year
  1988-08-16
• Entrez gene record
  7299
• RefSeq identity
  • NM_000372
• VEGA ID
  OTTHUMG00000167294
• Locus Specific Databases
  • Albinism Database
  • Mutations of the Tyrosinase Gene

Gene info

• Identity
  HGNC:12450
• Gene
  TYRP1
• Long gene name
  tyrosinase related protein 1
• Synonyms gene
  • TYRP
  • CAS2
• Synonyms
  • GP75
  • CATB
  • TRP
  • b-PROTEIN
  • OCA3
• GenBank acession
  • L33830
• Locus
  9p23
• Discovery year
  1991-09-04
• Entrez gene record
  7306
• Pubmed identfication
  • 9434945
• RefSeq identity
  • NM_000550
• VEGA ID
  OTTHUMG00000021034
• Locus Specific Databases
  • Mutations of the Tyrosinase-related Protein 1 Gene
  • Albinism Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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