TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)

  • Catalog number
    GEN604671
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    TWEAK
  • Other names
    tumor necrosis factor ligand superfamily member 12 proprotein; Tumor necrosis factor ligand superfamily member 12; tumor necrosis factor ligand superfamily member 12; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; tumor necrosis factor (ligand) superfamily, member 12; APO3 ligand; TNF-related weak inducer of apoptosis
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    TNFSF12; TNFSF12; APO3L; DR3LG; TWEAK; APO3L; DR3LG; TWEAK
  • Gene name synonims
    TNFSF12; TNFSF12; APO3L; DR3LG; TWEAK; APO3L; DR3LG; TWEAK
  • Other gene names
    TNFSF12; TNFSF12; APO3L; DR3LG; TWEAK; APO3L; DR3LG; TWEAK
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG1
  • Clone
    10B2504
  • Host organism
    Rat (Rattus norvegicus)
  • Source organism
    Mouse (Mus musculus)
  • Species reactivity
    Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes mouse TWEAK.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Affinity Purified by immunoaffinity chromatography.
  • Form Appearance
    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested applications
    Flow Cytometry (FC/FACS)
  • Description
    This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
  • Gene
    Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
  • Gene target
    TWEAK   TNF-related   Weak   Inducer   APO3   Ligand   APO3/DR3   Ligand   APO3L   CD255   DR3LG   FN14   HCG1991317   MGC129581   MGC20669   Tumor   Necrosis   Factor   Ligand   Superfamily   Member   TNFSF12   UNQ181/PRO207  
  • Gene symbol
    TNFSF12, TNF, TNFRSF1A, TNFRSF1B, LTBR, TNFRSF12A, TNFSF12-TNFSF13, TNFRSF25
  • Short name
    TWEAK (TNF- Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)
  • Technique
    apoptosis, apoptosis pathway
  • Alternative name
    Anti-TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)
  • Alternative technique
    celldeath
  • Alternative to gene target
    tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
  • Tissue
    tumor
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
    Tumor Stem Cell Assay
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
  • Tree numbers
    • E01.370.225.500.383.910
    • E01.370.225.500.388.930
    • E05.200.500.383.910
    • E05.200.500.388.930
    • E05.242.383.910
    • E05.242.417.500
    • E05.337.550.200.800
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Filters
TWEAK TNF Weak Inducer of Apoptosis APO3 Ligand APO3 DR3 Lig
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