Tweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor-inducible Immediate Early Response Protein 14, FGF-inducible 14, FN14, Tumor Necrosis Factor Receptor Superfamily Member 12A, TNFRSF12A, Type I Transmembrane Protein Fn14)
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Catalog numberMBS618212
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PricePlease ask
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Size50ug
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Alternative name1Anti-Tweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor-inducible Immediate Early Response Protein 14, FGF-inducible 14, FN14, Tumor Necrosis Factor Receptor Superfamily Member 12A, TNFRSF12A, Type I Transmembrane Protein Fn14)
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Alternative name2Tweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor-inducible Immediate Early Response Protein 14, FGF-inducible 14, FN14, Tumor Necrosis Factor Receptor Superfamily Member 12A, TNFRSF12A, Type I Transmembrane Protein Fn14)
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Alternative name3Tweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor-inducible Immediate Early Response Protein 14, FGF-inducible 14, FN14, Tumor Necrosis Factor Receptor Superfamily Member 12A, TNFRSF12A, Type I Transmembrane Protein Fn14)
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Alternative name4Tweak Receptor
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Alternative name5Anti -Tweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor-inducible Immediate Early Response Protein 14, FGF-inducible 14, FN14, Tumor Necrosis Factor Receptor Superfamily Member 12A, TNFRSF12A, Type I Transmembrane Protein Fn14)
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Other namestumor necrosis factor receptor superfamily member 12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily member 12A; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediate-early response protein 14; tumor necrosis factor receptor superfamily, member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; FGF-inducible 14; Tweak-receptor
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesTNFRSF12A; TNFRSF12A; FN14; CD266; TWEAKR; FN14; FGF-inducible 14; TweakR
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeN/A
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ClonePolyclonal antibody
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Host organismHost: Rabbit; Source: Human
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Species reactivityHuman
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Specificity and cross reactivityRecognizes Human Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A). Species Crossreactivity: Human.
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Purification methodN/A
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Form AppearanceSupplied as a liquid in PBS, 0.02% sodium azide.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested forWestern Blot (WB), Immunohistochemistry (IHC)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional descriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolTNFRSF12A, TNFSF12, FGF18, FGF17, IL12A, NUDT6, FGF4, FGF1
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Short nameTweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor- Immediate Early Response Protein 14, FGF- 14, FN14, Tumor Necrosis Factor Receptor Superfamily Member 12A, TNFRSF12A, I Transmembrane Protein Fn14)
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Alternative nameTweak Receptor (TWEAK R, TWEAKR, CD266, Fibroblast Growth Factor-inducible Immediate Early Response Protein 14, FGF-inducible 14, FN14, Tumor Necrosis Factor Receptor supergroup Member 12A, tumor necrosis factor receptor superfamily, member 12A, classification I Transmembrane Protein Fn14)
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Alternative to gene targettumor necrosis factor receptor superfamily, member 12A, TNFRSF12A and IDBG-11328 and ENSG00000006327 and 51330, protein binding, Cell surfaces, Tnfrsf12a and IDBG-143687 and ENSMUSG00000023905 and 27279, BT.20111 and IDBG-635818 and ENSBTAG00000012082 and 617439
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 12A
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 12A
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-20
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 12
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 12
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 18
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 17
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 12A
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Synonyms gene
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Synonyms gene name
- interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenudix hydrolase 6
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Synonyms gene name
- nudix (nucleoside diphosphate linked moiety X)-type motif 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nudix hydrolase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 4
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Synonyms gene
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Synonyms gene name
- heparin secretory transforming protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-04-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 1
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Synonyms gene
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Synonyms gene name
- fibroblast growth factor 1 (acidic)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
- Receptor ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data