TUSC2 Antibody

• Catalog number
  bs-5707R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TUSC2 Primary Polyclonal Antibody
• Also known as
  TUSC2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TUSC2
• Specificity
  This is a highly specific antibody against TUSC2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TUSC2
• Gene ID number
  11334
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C3orf11; FUS1; Fusion 1 protein; PAP; PDAP2; PDGFA associated protein 2; Tumor suppressor candidate 2; TUSC 2; TUSC2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TUSC2  
• Gene symbol
  TUSC2
• Short name
  Anti-TUSC2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TUSC2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17034
• Gene
  TUSC2
• Long gene name
  tumor suppressor 2, mitochondrial calcium regulator
• Synonyms gene
  • PDAP2
• Synonyms gene name
  • PDGFA associated protein 2
  • tumor suppressor candidate 2
• Synonyms
  • FUS1
  • PAP
  • C3orf11
• GenBank acession
  • AF055479
• Locus
  3p21.31
• Discovery year
  2003-09-25
• Entrez gene record
  11334
• Pubmed identfication
  • 8780057
  • 11593436
• RefSeq identity
  • NM_007275
• VEGA ID
  OTTHUMG00000156877

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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