Tumor Progression Locus 2 (Tpl2, TPL-2, Cancer Osaka thyroid oncogene, COT, mitogen-activated protein kinase kinase kinase 8)
-
Catalog numberGEN607580
-
PricePlease ask
-
Size100ul
-
-
Also known asTumor Progression Locus 2
-
Other namesN/A
-
CategoryAntibodies
-
SubcategoryMnoclonal antibodies
-
Gene nameN/A
-
Gene name synonimsN/A
-
Other gene namesN/A
-
ClonalityMonoclonal
-
Immunoglobulin isotypeIgG
-
Clone9E614
-
Host organismRabbit (Oryctolagus cuniculus)
-
Source organismHuman (Homo sapiens)
-
Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivityRecognizes human Tpl2.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification methodSupernatant
-
Form AppearanceSupplied in a liquid form in 50mM Tris-Glycine, pH 7.4, 0.15 M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
-
ConcentrationN/A
-
Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
-
Tested applicationsWestern Blot (WB)
-
Gene target
-
Gene symbolMAP3K8, CROT, CCDC83, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
-
Short nameTumor Progression Locus 2 (Tpl2, TPL-2, Cancer Osaka thyroid oncogene, COT, mitogen-activated protein kinase kinase kinase 8)
-
Alternative nameAnti-Tumor Progression Locus 2 (Tpl2, TPL-2, Cancer Osaka thyroid oncogene, COT, mitogen-activated protein kinase kinase kinase 8)
-
Tissuethyroid, tumor
-
Diseasecancer
-
Gene info
-
Identity
-
Gene
-
Long gene namemitogen-activated protein kinase kinase kinase 8
-
Synonyms gene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-09-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Mitogen-activated protein kinase kinase kinases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecarnitine O-octanoyltransferase
-
Synonyms
-
Locus
-
Discovery year2000-06-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecoiled-coil domain containing 83
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2006-03-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 7-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR7 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 329-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-11
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR329 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 512-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR506 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 521-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR515 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1289-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1289 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 509-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2007-10-24
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR506 family
Gene info
-
Identity
-
Gene
-
Long gene namekeratin associated protein 13-2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-02-21
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Keratin associated proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
-
Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data