TTC21B Antibody

• Catalog number
  bs-12069R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TTC21B Primary Polyclonal Antibody
• Also known as
  TTC21B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TTC21B
• Specificity
  This is a highly specific antibody against TTC21B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1285-1316/1316
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TTC21B
• Gene ID number
  79809
• Swiss Prot
  Q7Z4L5
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ATD4; JBTS11; Nbla10696; NPHP12; Putative protein product of Nbla10696; Tetratricopeptide repeat protein 21B; THM1; TPR repeat protein 21B; TT21B_HUMAN; Ttc21b.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TTC21B  
• Gene symbol
  TTC21B-AS1, TTC21B
• Short name
  Anti-TTC21B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TTC21B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:41115
• Gene
  TTC21B-AS1
• Long gene name
  TTC21B antisense RNA 1
• Locus
  2q24.3
• Discovery year
  2013-10-15
• Entrez gene record
  100506134
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154082

Gene info

• Identity
  HGNC:25660
• Gene
  TTC21B
• Long gene name
  tetratricopeptide repeat domain 21B
• Synonyms
  • FLJ11457
  • JBTS11
  • NPHP12
  • IFT139B
  • THM1
  • FAP60
  • FLA17
• GenBank acession
  • AB082523
• Locus
  2q24.3
• Discovery year
  2005-01-26
• Entrez gene record
  79809
• Pubmed identfication
  • 12056414
  • 21258341
• RefSeq identity
  • NM_024753
• Classification
  • Tetratricopeptide repeat domain containing
  • IFT-A complex
• VEGA ID
  OTTHUMG00000154083

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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