TNXB Antibody

• Catalog number
  R32015
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TNXB
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the TNXB antibody should be determined by the researcher.
• Intented use
  This TNXB antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P22105
• Purity
  Antigen affinity
• Description
  Tenascin X (TN-X), also known as hexabrachion-like protein, is a glycoprotein that is expressed in connective tissues including skin, joints and muscles. In humans, tenascin X is encoded by the TNXB gene. This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  Amino acids DLRAVAVSGLDPARKYKFLLFGLQNGKRH of human TNXB were used as the immunogen for the TNXB antibody.
• Storage
  After reconstitution, the TNXB antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TNXB  
• Gene symbol
  TNXB
• Short name
  Anti-TNXB
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TNXB
• Alternative technique
  antibodies
• Alternative to gene target
  tenascin XB, EDS3 and HXBL and TENX and TN-X and TNX and TNXB1 and TNXB2 and TNXBS and VUR8 and XB and XBS, TNXB and IDBG-79909 and ENSG00000168477 and 7148, heparin binding, Extracellular, Tnxb and IDBG-172715 and ENSMUSG00000033327 and 81877, TNXB and IDBG-633174 and ENSBTAG00000001444 and 282654

Gene info

• Identity
  HGNC:11976
• Gene
  TNXB
• Long gene name
  tenascin XB
• Synonyms gene
  • TNXB1
  • TNXB2
• Synonyms
  • TNXBS
  • XBS
  • XB
• GenBank acession
  • X71923
• Locus
  6p21.33-p21.32
• Discovery year
  2000-07-25
• Entrez gene record
  7148
• Pubmed identfication
  • 8530023
• RefSeq identity
  • NM_019105
• Classification
  • Tenascins
• VEGA ID
  OTTHUMG00000031088

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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