TNF protein Bovine His tag

Category

Proteins
Antibody Subtype

Conjugated Proteins
Area of research

Cytokines & Growth Factors
Reactivity

Bovine
Residues

LRSSSQASSNKPVAHVVADINSPGQLRWWDSYANALMANGVKLEDNQLVVPADGLYLIYSQVLFRGQGCP STPLFLTHTISRIAVSYQTKVNILSAIKSPCHRETPEWAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPD YLDYAESGQVYFGIIAL
Conjugate Tag

His tag
Type of protein

Recombinant
Expression System

Escherichia coli
Grade Purity

Grater than 95% pure
Source

His-fusion expressed as an inclusion body
Form Buffer

Provided in liquid form in 20 mM Tris-Hcl, 0.5MNaCl, 10% glycerin (pH 8.0) and 200 mM Imidazole
Storage

Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles
Tested for

ELISA; SDS-PAGE; WB
URL
More info
Conjugation

histidine
Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

Gene target

TNF protein His tag
Gene symbol

TNF, TNFRSF1A, TNFRSF1B, LTBR
Short name

TNF protein His tag
Technique

Tags
Label

His
Species

Bovine, Bos Taurus genes are available form the Bovine Genome database.
Alternative name

Purified recombinant TNF protein (Bovine) (His tag)
Alternative to gene target

tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943

Identity

HGNC:11916
Gene

TNFRSF1A
Long gene name

TNF receptor superfamily member 1A
Synonyms gene
- TNFR1
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
Synonyms
- TNF-R
- TNFAR
- TNFR60
- TNF-R-I
- CD120a
- TNF-R55
GenBank acession
- M75866
Locus

12p13.31
Discovery year

1991-01-15
Entrez gene record

7132
Pubmed identfication
- 1655358
- 2158863
RefSeq identity
- NM_001065
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
VEGA ID

OTTHUMG00000168267
Locus Specific Databases
- INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
- LRG_193

Identity

HGNC:11917
Gene

TNFRSF1B
Long gene name

TNF receptor superfamily member 1B
Synonyms gene
- TNFR2
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
Synonyms
- TNFBR
- TNFR80
- TNF-R75
- TNF-R-II
- p75
- CD120b
GenBank acession
- M32315
Locus

1p36.22
Discovery year

1991-01-15
Entrez gene record

7133
Pubmed identfication
- 2158863
- 8702885
RefSeq identity
- NM_001066
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000001829