TLR10 Antibody

• Catalog number
  R31061
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TLR10
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the TLR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TLR10 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9BXR5
• Purity
  Antigen affinity
• Description
  Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al.(2005) determined that the gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al.(2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM(TICAM2), or TRIF (TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.
• Immunogen
  An amino acid sequence from the N-terminus of human Toll-like receptor 10 (DLKTFEFNKELRYLD) was used as the immunogen for this TLR10 antibody.
• Storage
  After reconstitution, the TLR10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR10  
• Gene symbol
  TLR10
• Short name
  Anti-TLR10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TLR10
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 10, TLR10 and IDBG-13548 and ENSG00000174123 and 81793, protein binding, Plasma membranes, TLR10 and IDBG-641604 and ENSBTAG00000014042 and 539791

Gene info

• Identity
  HGNC:15634
• Gene
  TLR10
• Long gene name
  toll like receptor 10
• Synonyms gene name
  • toll-like receptor 10
• Synonyms
  • CD290
• GenBank acession
  • AF296673
• Locus
  4p14
• Discovery year
  2001-04-27
• Entrez gene record
  81793
• Pubmed identfication
  • 11267672
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000128578

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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