THOP1/Thimet Oligopeptidase Antibody, FITC Conjugated

#

• Catalog number
  bs-11683R-FITC
• Price:

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• Size
  0.1ml

# #

• Long name
  THOP1/Thimet Oligopeptidase Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  THOP1/Thimet Oligopeptidase
• Specificity
  This is a highly specific antibody against THOP1/Thimet Oligopeptidase.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human Thimet Oligopeptidase
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Thimet oligopeptidase, also designated soluble metallo-endopeptidase, is a cytoplasmic protein belonging to the peptidase M3 family. The gene for the protein maps against chromosome 19q13.3. Thimet oligopeptidase can degrade the b-Amyloid precursor protein and generate amyloidogenic fragments. It is important in cytoplasmic peptide degradation and involved in metabolism of neuropeptides that are less than 20 amino acids in length. Thimet oligopeptidase is highly expressed in testis but can also be detected in liver, lung and kidney.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  Endopeptidase 24.15; EP24.15; MEPD_HUMAN; MP78; Thimet oligopeptidase 1; Thimet oligopeptidase; Thop1; THOP1_HUMAN; EC 3.4.24.15.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

#

• Gene target
  THOP1/Thimet   Oligopeptidase   Conjugated  
• Gene symbol
  THOP1
• Short name
  Anti-THOP1/Thimet Oligopeptidase
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-THOP1/Thimet Oligopeptidase PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  thimet oli this GO peptidase 1, EP24.15 and MEPD_HUMAN and MP78 and TOP, THOP1 and IDBG-16324 and ENSG00000172009 and 7064, metal ion binding, Cytoplasm, Thop1 and IDBG-176844 and ENSMUSG00000004929 and 50492, THOP1 and IDBG-644496 and ENSBTAG00000020446 and 510889

Gene info

• Identity
  HGNC:11793
• Gene
  THOP1
• Long gene name
  thimet oligopeptidase 1
• Locus
  19p13.3
• Discovery year
  1995-07-06
• Entrez gene record
  7064
• Pubmed identfication
  • 9790774
  • 32847123
• Classification
  • M3 metallopeptidase family
• VEGA ID
  OTTHUMG00000180492

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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