Tankyrase Antibody

• Catalog number
  bs-9104R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Tankyrase Primary Polyclonal Antibody
• Also known as
  Tankyrase PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Tankyrase
• Specificity
  This is a highly specific antibody against Tankyrase.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1140-1171/1327
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tankyrase
• Gene ID number
  8658
• Swiss Prot
  O95271
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TIN1; ARTD5; PARPL; TINF1; TNKS1; pART5; PARP5A; PARP-5a; Tankyrase-1; TANK1; ADP-ribosyltransferase diphtheria toxin-like 5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I; TNKS
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Tankyrase  
• Gene symbol
  TNKS1BP1, TNKS, TNKS2
• Short name
  Anti-Tankyrase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Tankyrase Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19081
• Gene
  TNKS1BP1
• Long gene name
  tankyrase 1 binding protein 1
• Synonyms gene name
  • tankyrase 1 binding protein 1, 182kDa
• Synonyms
  • TAB182
  • KIAA1741
  • FLJ45975
• GenBank acession
  • AB051528
• Locus
  11q12.1
• Discovery year
  2002-08-06
• Entrez gene record
  85456
• Pubmed identfication
  • 11854288
• RefSeq identity
  • NM_033396
• Classification
  • CCR4-NOT transcription complex
• VEGA ID
  OTTHUMG00000167022

Gene info

• Identity
  HGNC:11941
• Gene
  TNKS
• Long gene name
  tankyrase
• Synonyms gene name
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
• Synonyms
  • TIN1
  • TINF1
  • TNKS1
  • PARP-5a
  • PARP5A
  • pART5
  • ARTD5
• Synonyms name
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 1
• GenBank acession
  • AF082556
• Locus
  8p23.1
• Discovery year
  1999-01-08
• Entrez gene record
  8658
• Pubmed identfication
  • 9822378
  • 10198177
• RefSeq identity
  • NM_003747
• Classification
  • Poly(ADP-ribose) polymerases
  • Sterile alpha motif domain containing
  • Ankyrin repeat domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000090481

Gene info

• Identity
  HGNC:15677
• Gene
  TNKS2
• Long gene name
  tankyrase 2
• Synonyms gene name
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
• Synonyms
  • TNKL
  • TANK2
  • PARP-5b
  • PARP-5c
  • PARP5B
  • PARP5C
  • pART6
  • ARTD6
• Synonyms name
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 2
• GenBank acession
  • AF342982
• Locus
  10q23.32
• Discovery year
  2001-05-10
• Entrez gene record
  80351
• RefSeq identity
  • NM_025235
• Classification
  • Poly(ADP-ribose) polymerases
  • Sterile alpha motif domain containing
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000018747

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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