SUMO2/3 Antibody

• Catalog number
  F42027-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SUMO2/3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IF, WB, IHC, ELISA
• Recommended dilutions
  Immunofluorescence: 1:25-100,Western blot: 1:1000,IHC (FFPE): 1:50-100
• Notes
  Titration of the SUMO2/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SUMO2/3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P55854
• Purity
  Purified
• Description
  SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
• Immunogen
  A portion of amino acids 49-81 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.
• Storage
  Aliquot the SUMO2/3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SUMO2/3  
• Gene symbol
  SUMO2
• Short name
  Anti-SUMO2/3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to SUMO2/3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11125
• Gene
  SUMO2
• Long gene name
  small ubiquitin like modifier 2
• Synonyms gene
  • SMT3H2
• Synonyms gene name
  • SMT3 (suppressor of mif two 3, yeast) homolog 2
  • SMT3 suppressor of mif two 3 homolog 2 (yeast)
  • SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
• Synonyms
  • SMT3B
• Locus
  17q25
• Discovery year
  1997-01-29
• Entrez gene record
  6613
• Pubmed identfication
  • 8630065
• RefSeq identity
  • NM_006937
• VEGA ID
  OTTHUMG00000179481

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products