Sumo 1 Antibody

• Catalog number
  PA2220
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Sumo 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat Predicted to work with: mouse
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human Sumo 1(15-30aa DKKEGEYIKLKVIGQD), identical to the related mouse and rat sequences.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Sumo 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Sumo 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Small ubiquitin-related modifier 1(SUMO1), also called SMT3C or PIC1 is a protein that in humans is encoded by the SUMO1 gene. This gene is mapped to 2q33.1. This gene encodes a protein that is a member of the SUMO(small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene.
• Related articles
  1. Alkuraya, F. S., Saadi, I., Lund, J. L., Turbe-Doan, A., Morton, C. C., Maas, R. L. SUMO1 haploinsufficiency leads to cleft lip and palate. Science 313: 1751 only, 2006. 2. Kho, C., Lee, A., Jeong, D., Oh, J. G., Chaanine, A. H., Kizana, E., Park, W. J., Hajjar, R. J. SUMO1-dependent modulation of SERCA2a in heart failure. Nature 477: 601-605, 2011. 3. Martin, S., Nishimune, A., Mellor, J. R., Henley, J. M. SUMOylation regulates kainate-receptor-mediated synaptic transmission. Nature 447: 321-325, 2007.
• Gene Name
  SUMO1
• Protein Name
  Small ubiquitin-related modifier 1
• Gene Full Name
  small ubiquitin-like modifier 1
• Synonyms
  GAP modifying protein 1 antibody|GAP-modifying protein 1 antibody|GMP 1 antibody|GMP1 antibody|OFC10 antibody|PIC 1 antibody|PIC1 antibody|SENP2 antibody|Sentrin 1 antibody|Sentrin antibody|Small ubiquitin related modifier 1 antibody|Small ubiquitin-like modifier 1 antibody|Small ubiquitin-related modifier 1 antibody|SMT3 antibody|SMT3 homolog 3 antibody|SMT3 suppressor of mif two 3 homolog 1 antibody|SMT3, yeast, homolog 3 antibody|SMT3C antibody|SMT3H3 antibody|SUMO-1 antibody|Sumo1 antibody|SUMO1_HUMAN antibody|Ubiquitin homology domain protein PIC1 antibody|Ubiquitin Like 1 antibody|Ubiquitin like protein SMT3C antibody|Ubiquitin like protein UBL1 antibody|Ubiquitin-homology domain protein PIC1 antibody|Ubiquitin-like protein SMT3C antibody|Ubiquitin-like protein UBL1 antibody|UBL 1 antibody|UBL1 antibody
• Uniprot ID
  P63165
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Sumo  
• Gene symbol
  SENP8, SIMC1, SENP1
• Short name
  Sumo 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Sumo 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:22992
• Gene
  SENP8
• Long gene name
  SUMO peptidase family member, NEDD8 specific
• Synonyms gene
  • PRSC2
• Synonyms gene name
  • protease, cysteine, 2 (NEDD8 specific)
  • SUMO/sentrin specific protease family member 8
  • SUMO/sentrin specific peptidase family member 8
  • SUMO/sentrin peptidase family member, NEDD8 specific
• Synonyms
  • NEDP1
  • DEN1
  • HsT17512
• Synonyms name
  • NEDD8-specific protease 1
  • sentrin/SUMO-specific protease SENP8
  • deneddylase 1
• GenBank acession
  • BC031411
• Locus
  15q23
• Discovery year
  2003-09-02
• Entrez gene record
  123228
• Pubmed identfication
  • 12730221
  • 12759362
• RefSeq identity
  • NM_145204
• Classification
  • SUMO specific peptidases
• VEGA ID
  OTTHUMG00000133441

Gene info

• Identity
  HGNC:24779
• Gene
  SIMC1
• Long gene name
  SUMO interacting motifs containing 1
• Synonyms gene
  • C5orf25
• Synonyms gene name
  • chromosome 5 open reading frame 25
  • SUMO-interacting motifs containing 1
• Synonyms
  • FLJ44216
  • OOMA1
  • PLEIAD
• Synonyms name
  • oocyte maturation associated 1
  • platform element for inhibition of autolytic degradation
• GenBank acession
  • BC037298
• Locus
  5q35.2
• Discovery year
  2006-04-10
• Entrez gene record
  375484
• Pubmed identfication
  • 23086935
  • 23707407
• RefSeq identity
  • NM_198567
• VEGA ID
  OTTHUMG00000130663

Gene info

• Identity
  HGNC:17927
• Gene
  SENP1
• Long gene name
  SUMO specific peptidase 1
• Synonyms gene name
  • SUMO1/sentrin specific protease 1
  • SUMO1/sentrin specific peptidase 1
• GenBank acession
  • AF149770
• Locus
  12q13.11
• Discovery year
  2004-02-20
• Entrez gene record
  29843
• Pubmed identfication
  • 10652325
  • 14563852
• RefSeq identity
  • NM_014554
• Classification
  • SUMO specific peptidases
• VEGA ID
  OTTHUMG00000169896

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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