Stattic,STAT3 inhibitor

• Catalog number
  SIH-554-2X5MG
• Price
  Please ask
• Size
  2X5 mg

• Research Area s
  Stem Cells , Neuroscience , Neurodegeneration , Alzheimer's Disease , Cell Signaling , Epigenetics and Nuclear Signaling , DNA/RNA , DNA Synthesis , Cell Signaling , Epigenetics and Nuclear Signaling , Transcription , Transcription Factors , Cancer
• Category
  Small Molecules
• Product Type
  Inhibitor
• CAS No
  19983-44-9
• MolecularFormula
  C8H5NO4S
• Molecular Weight
  211.2
• Purity
  >98% (TLC); NMR (Conforms)
• Solubility
  May be dissolved in DMSO (10 mg/ml); or ethanol (1 mg/ml)
• Appearance
  Light yellow powder
• Storage Temperature
  -20°C
• Shipping Temperature
  Shipped Ambient
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Stattic   STAT3   inhibitor  
• Gene symbol
  STAT3
• Short name
  Stattic STAT3 inhibitor
• Alternative name
  Stattic,signal transducer and activator on transcription 3 (acute-phase response factor) suppressor
• Alternative to gene target
  signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541

Gene info

• Identity
  HGNC:11364
• Gene
  STAT3
• Long gene name
  signal transducer and activator of transcription 3
• Synonyms gene name
  • signal transducer and activator of transcription 3 (acute-phase response factor)
• Synonyms
  • APRF
• GenBank acession
  • BC014482
• Locus
  17q21.2
• Discovery year
  1995-11-08
• Entrez gene record
  6774
• Pubmed identfication
  • 7512451
• RefSeq identity
  • NM_139276
  • NM_003150
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000150645
• Locus Specific Databases
  • STAT3base: Mutation registry for Hyper-IgE syndrome
  • LRG_112

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