SIRT5 Antibody, ALEXA FLUOR 555

• Catalog number
  bs-9456R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  SIRT5 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-SIRT5 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SIRT5
• Specificity
  This is a highly specific antibody against SIRT5.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  120-170/310
• Subcellular location
  Mitochondrion
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIRT5
• Gene ID Number
  23408
• Swiss Prot
  Q9NXA8
• Tested applications
  IF(IHC-P), IF(IHC-F)
• Recommended dilutions
  IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  SIR2L5; NAD-dependent protein deacylase sirtuin-5, mitochondrial; Regulatory protein SIR2 homolog 5; SIR2-like protein 5; SIRT5
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  SIRT5  
• Gene symbol
  SIRT5
• Short name
  Anti-SIRT5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  SIRT5 Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14933
• Gene
  SIRT5
• Long gene name
  sirtuin 5
• Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 5
  • sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
• GenBank acession
  • AF083110
• Locus
  6p23
• Discovery year
  2001-03-20
• Entrez gene record
  23408
• Pubmed identfication
  • 10381378
• Classification
  • Sirtuins
• VEGA ID
  OTTHUMG00000014278

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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