PTPN6(Tyr536) Antibody
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Catalog numberbs-5577R
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Price:
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Size0.1ml
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Long namePTPN6(Tyr536) Primary Polyclonal Antibody
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Also known asPTPN6(Tyr536) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPTPN6 Tyr536
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SpecificityThis is a highly specific antibody against PTPN6 Tyr536.
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Modification sPhosphorylation
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Modification site sTyr536
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range515-555/595
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Subcellular locationCytoplasm, Nucleus
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SourceKLH conjugated synthetic phosphopeptide derived from human PTPN6 around the phosphorylation site of Tyr536 [SE(p-Y)GN]
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Gene ID number5777
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenSHP1 is a member of the non receptor protein tyrosine phosphatase subfamily. The PTP family comprises of at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is cytosolic. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. SHP1 is implicated in the control of tyrosine kinase signalling pathways in cellular proliferation, with a potential role in cancer.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesSHP-1Tyr536; PTPN6phospho Y536; SHP1phospho Y536; 70 kda SHP1L protein; HCP; HCPH; Hematopoietic cell phosphatase; Hematopoietic cell protein tyrosine phosphatase; Hematopoietic cell protein-tyrosine phosphatase; HPTP1C; Protein tyrosine phosphatase 1C; Protein tyrosine phosphatase non receptor type 6; Protein tyrosine phosphatase SHP1; PTP1C; PTPN6; SH PTP 1; SHP1; SHP1L; PTN6_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPTPN6
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Short nameAnti-PTPN6 Tyr536
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePTPN6(Tyr536) Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetprotein tyrosine phosphatase, non-receptor type 6, HCP and HCPH and HPTP1C and PTP-1C and SH-PTP1 and SHP-1 and SHP-1L and SHP1, PTPN6 and IDBG-15719 and ENSG00000111679 and 5777, SH2 domain binding, nuclei, Ptpn6 and IDBG-187635 and ENSMUSG00000004266 and 15170, PTPN6 and IDBG-640141 and ENSBTAG00000020294 and 512312
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Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase non-receptor type 6
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Synonyms
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Locus
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Discovery year1992-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data