-
Description
Histochemical kit
-
Summary
• Species reactivity- Mammalian • Kit size- 250 stainings • Applications- The Senescence Detection Kit is designed to histochemically detect specific senescence marker in distinct pH in cultured cells and tissue sections.
-
Sample Type
Cell culture cells, tissues
-
Features Benefits
• Simple procedure; takes around than 30 minutes • Fast and convenient • The specific histochemical marker is only present in senescent cells and is not found in presenescent, quiescent or immortal cells.
-
Storage Conditions
-20°C
-
Shipping Conditions
gel pack
-
Shelf life
12 months
-
Background
Senescence is thought to be a tumor suppressive mechanism and an underlying cause of aging. Senescence represents an arrested state in which the cells remain viable, but not stimulated to divide by serum or passage in culture. Senescent cells display increase of cell size, senescence-associated expression of β-galactosidase (SA-β-Gal) activity, and altered patterns of gene expression. The Senescence detection kit is designed to histochemically detect SA-β-Gal activity in cultured cells and tissue sections, a known characteristic of senescent cells. The SA-β-Gal is present only in senescent cells and is not found in presenescent, quiescent or immortal cells.
-
-
Additional description
The detections of the targets with this kit is a type of test that can be performed on any target containing biological samples after clean up of interfering agents. The assay must be performed following the protocol.
