RUNX1 + RUNX2 Antibody

• Catalog number
  bs-1134R
• Price
  Please ask
• Size
  0.1ml

• Long name
  RUNX1 + RUNX2 Primary Polyclonal Antibody
• Also known as
  RUNX1 + RUNX2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  RUNX1+RUNX2
• Specificity
  This is a highly specific antibody against RUNX1+RUNX2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  200-250/521
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RUNX2
• Gene ID number
  860
• Swiss Prot
  Q13950
• Tested Applications
  WB, IHC-P, IF(IHC-P), IF(ICC)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1; Runt-related transcription factor 2; Acute myeloid leukemia 3 protein; Core-binding factor subunit alpha-1; Oncogene AML-3; Osteoblast-specific transcription factor 2; Polyomavirus enhancer-binding protein 2 alpha A subunit; PEA2-alpha A; PEBP2-alpha A; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A subunit; RUNX2; PEBP2A
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RUNX1   RUNX2  
• Gene symbol
  RUNX2-AS1, RUNX1-IT1, RUNX1, RUNX2
• Short name
  Anti-RUNX1+RUNX2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  RUNX1 + RUNX2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  runt-related transcription factor 1, AML1 and AML1-EVI-1 and AMLCR1 and CBFA2 and EVI-1 and PEBP2aB, RUNX1 and IDBG-2825 and ENSG00000159216 and 100506403,101928269,861, repressing transcription factor binding, nuclei, Runx1 and IDBG-177713 and ENSMUSG00000022952 and 12394, RUNX1 and IDBG-640443 and ENSBTAG00000004742 and 529631

Gene info

• Identity
  HGNC:53512
• Gene
  RUNX2-AS1
• Long gene name
  RUNX2 antisense RNA 1
• Locus
  6p21.1
• Discovery year
  2017-05-12
• Entrez gene record
  105375077
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:16623
• Gene
  RUNX1-IT1
• Long gene name
  RUNX1 intronic transcript 1
• Synonyms gene
  • C21orf96
• Synonyms gene name
  • chromosome 21 open reading frame 96
  • RUNX1 intronic transcript 1 (non-protein coding)
• Synonyms
  • FLJ20856
• GenBank acession
  • AK024509
• Locus
  21q22.12
• Discovery year
  2003-10-01
• Entrez gene record
  80215
• Pubmed identfication
  • 32487998
• RefSeq identity
  • NR_026812
• Classification
  • Intronic transcripts

Gene info

• Identity
  HGNC:10471
• Gene
  RUNX1
• Long gene name
  RUNX family transcription factor 1
• Synonyms gene
  • AML1
  • CBFA2
• Synonyms gene name
  • acute myeloid leukemia 1
  • runt-related transcription factor 1
  • runt related transcription factor 1
• Synonyms
  • PEBP2A2
  • AMLCR1
• Synonyms name
  • aml1 oncogene
• GenBank acession
  • X79549
• Locus
  21q22.12
• Discovery year
  1991-08-20
• Entrez gene record
  861
• Pubmed identfication
  • 1427868
  • 7835892
• Classification
  • Runt-related transcription factors
• VEGA ID
  OTTHUMG00000086299
• Locus Specific Databases
  • LRG_482

Gene info

• Identity
  HGNC:10472
• Gene
  RUNX2
• Long gene name
  RUNX family transcription factor 2
• Synonyms gene
  • CCD
  • CBFA1
  • CCD1
• Synonyms gene name
  • runt-related transcription factor 2
  • runt related transcription factor 2
• Synonyms
  • AML3
  • PEBP2A1
  • PEBP2aA1
• GenBank acession
  • AF001450
• Locus
  6p21.1
• Discovery year
  1994-11-02
• Entrez gene record
  860
• Pubmed identfication
  • 7835892
• RefSeq identity
  • NM_004348
• Classification
  • Runt-related transcription factors
• VEGA ID
  OTTHUMG00000014774

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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