RNF142 Antibody

• Catalog number
  bs-9156R
• Price
  Please ask
• Size
  0.1ml

• Long name
  RNF142 Primary Polyclonal Antibody
• Also known as
  RNF142 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  RNF142
• Specificity
  This is a highly specific antibody against RNF142.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SH3MD2/RNF142
• Gene ID number
  57630
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Plenty of SH3 domains; Plenty of SH3s; POSH; Ring finger protein 142; RNF 142; RNF142; SH3 domain containing ring finger 1; SH3 domain containing RING finger protein 1; SH3MD2; SH3 multiple domains 2; SH3RF1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RNF142  
• Gene symbol
  SH3RF1
• Short name
  Anti-RNF142
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  RNF142 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17650
• Gene
  SH3RF1
• Long gene name
  SH3 domain containing ring finger 1
• Synonyms gene
  • SH3MD2
• Synonyms gene name
  • SH3 multiple domains 2
• Synonyms
  • POSH
  • RNF142
  • KIAA1494
• Synonyms name
  • plenty of SH3 domains
• GenBank acession
  • BC033203
• Locus
  4q32.3-q33
• Discovery year
  2003-12-01
• Entrez gene record
  57630
• Pubmed identfication
  • 9482736
• RefSeq identity
  • NM_020870
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000161010

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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