RFC1 Antibody

• Catalog number
  bs-11304R
• Price
  Please ask
• Size
  0.1ml

• Long name
  RFC1 Primary Polyclonal Antibody
• Also known as
  RFC1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  RFC1
• Specificity
  This is a highly specific antibody against RFC1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  420-465/1148
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RFC1
• Gene ID number
  5981
• Swiss Prot
  P35251
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  A1; RFC; PO-GA; RECC1; MHCBFB; RFC140; Replication factor C subunit 1; Activator 1 140 kDa subunit; A1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA-binding protein PO-GA; Replication factor C 140 kDa subunit; RF-C 140 kDa subunit; Replication factor C large subunit; RFC1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RFC1  
• Gene symbol
  SLC19A1, RFC1
• Short name
  Anti-RFC1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  RFC1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10937
• Gene
  SLC19A1
• Long gene name
  solute carrier family 19 member 1
• Synonyms gene name
  • solute carrier family 19 (folate transporter), member 1
• Synonyms
  • FOLT
  • RFC1
• Synonyms name
  • reduced folate carrier 1
  • Folate transporter 1
• GenBank acession
  • U15939
• Locus
  21q22.3
• Discovery year
  1995-05-01
• Entrez gene record
  6573
• Pubmed identfication
  • 9570943
• Classification
  • Solute carriers
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000090397

Gene info

• Identity
  HGNC:9969
• Gene
  RFC1
• Long gene name
  replication factor C subunit 1
• Synonyms gene name
  • replication factor C (activator 1) 1 (145kD)
  • replication factor C (activator 1) 1, 145kDa
• Synonyms
  • A1
  • PO-GA
  • RFC140
  • MHCBFB
• GenBank acession
  • L23320
• Locus
  4p14
• Discovery year
  1994-10-14
• Entrez gene record
  5981
• Pubmed identfication
  • 8114700
• RefSeq identity
  • NM_002913
• Classification
  • AAA ATPases
• VEGA ID
  OTTHUMG00000099363

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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