Recombinant Three Prime Repair Exonuclease 1 (TREX1)

• Catalog number
  RPC810Hu01-500ug
• Price
  Please ask
• Size
  500ug

• Description
  Recombinant Human Three Prime Repair Exonuclease 1 expressed in: E.coli
• Specifications
  Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Arg6~Glu369; Purity: > 95%; Endotoxin level:
• Additional_information
  Uniprot ID: Q9NSU2; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 42.2kDa; Isoelectric Point: 8.8
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Three   Prime   Repair   Exonuclease   TREX1  
• Gene symbol
  TREX1
• Short name
  Recombinant Three Prime Repair Exonuclease 1 (TREX1)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Rec. Three Prime Repair Exonuclease 1 (TREX1)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:12269
• Gene
  TREX1
• Long gene name
  three prime repair exonuclease 1
• Synonyms gene
  • AGS1
• Synonyms gene name
  • Aicardi-Goutieres syndrome 1
• Synonyms
  • DRN3
• GenBank acession
  • AF151105
• Locus
  3p21.31
• Discovery year
  2000-05-17
• Entrez gene record
  11277
• Pubmed identfication
  • 10391904
  • 10393201
  • 16845398
• RefSeq identity
  • NM_033629
• Classification
  • Exonucleases
  • SET complex
• VEGA ID
  OTTHUMG00000156205
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_282

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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