Recombinant Mouse CD302 / CLEC13A Protein (Fc tag)
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Catalog number
PKSM040534-20µg
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Price
Please ask
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Size
20µg
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Synonym
1110055L24Rik;AI159627
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Activity
NA
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Sequence
Met 1-His 156
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Fusion tag
C-Fc
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Accession
Q9DCG2-2
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 93 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
42.6 kDa
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AP Mol Mass
48 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CD302, LY75-CD302
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Short name
Recombinant Mouse CD302 / CLEC13A Protein (Fc tag)
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Technique
Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
mouse
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Label
Fc Tag
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse CD302 molecule / CLEC13A Protein (fragment c detection labelled)
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Alternative technique
rec, murine
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Alternative to gene target
CD302 molecule, BIMLEC and CLEC13A and DCL-1 and DCL1, CD302 and IDBG-403891 and ENSG00000241399 and 9936, carbohydrate binding, Plasma membranes, Cd302 and IDBG-172983 and ENSMUSG00000060703 and 66205, CD302 and IDBG-641458 and ENSBTAG00000038195 and 100126272
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Gene info
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Identity
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Gene
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Long gene name
CD302 molecule
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Synonyms gene name
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2005-02-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
LY75-CD302 readthrough
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Locus
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Discovery year
2011-04-19
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Entrez gene record
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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