Recombinant Human TSPAN1 Protein (aa 110-211, Fc tag) 100µg
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Catalog numberPKSH030743-100µg
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PricePlease ask
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Size100µg
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SynonymNET1;TM4C;TM4SF;TSPAN1
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ActivityNA
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SequenceTyr110-Asn211
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Fusion tagN-Fc
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AccessionO60635
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Expressed HostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity＞95 % as determined by SDS-PAGE
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Endotoxin＜1.0 EU per µg as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass39.1 kDa
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AP Mol Mass43-53 kDa
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FormulationLyophilized from sterile PBS, pH 7.4
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ReconstitutionPlease refer to it for detailed information.
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BackgroundTSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone; in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolAFAP1, TSPAN1, MIR211, SF3B6, DLG2, RNVU1-20, OR7E110P
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Short nameRecombinant TSPAN1 Protein (aa 110-211, Fc tag) 100µg
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TechniqueRecombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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LabelFc Tag
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens TSPAN1 Protein (aa 110-211, fragment c detection labelled) 100µg
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameactin filament associated protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametetraspanin 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-01-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tetraspanins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 211
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR204/211 family
Gene info
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Identity
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Gene
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Long gene namesplicing factor 3b subunit 6
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Synonyms gene name
- splicing factor 3b, subunit 6, 14kDa
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Synonyms
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Synonyms name
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Locus
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Discovery year2014-02-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SF3b complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namediscs large MAGUK scaffold protein 2
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Synonyms gene name
- discs, large homolog 2, chapsyn-110 (Drosophila)
- discs, large homolog 2 (Drosophila)
- discs large homolog 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
- Membrane associated guanylate kinases
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRNA, variant U1 small nuclear 20
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Synonyms
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Locus
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Discovery year2013-04-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Variant U1 small nuclear RNAs
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 7 subfamily E member 110 pseudogene
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Synonyms gene
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Synonyms gene name
- olfactory receptor, family 7, subfamily E, member 110 pseudogene
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Synonyms
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Locus
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Discovery year2001-03-28
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Entrez gene record
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Classification
- Olfactory receptors, family 7
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
