Recombinant Human Serglycin / SRGN Protein (His tag)

• Catalog number
  PKSH030586-20µg
• Price
  Please ask
• Size
  20µg

• Synonym
  PPG;PRG;PRG1
• Activity
  NA
• Sequence
  Met1-Leu158
• Fusion tag
  C-His
• Accession
  CAA34900.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞95 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  16.1 kDa
• AP Mol Mass
  16.1 kDa
• Formulation
  Lyophilized from sterile PBS, pH7.4
• Background
  SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
• Technical data
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Serglycin   SRGN   Protein   His   tag  
• Gene symbol
  SRGN
• Short name
  Recombinant Serglycin / SRGN Protein (His tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Serglycin / serglycin Protein (histidine detection labelled)
• Alternative technique
  rec
• Alternative to gene target
  serglycin, PPG and PRG and PRG1, SRGN and IDBG-76481 and ENSG00000122862 and 5552, collagen binding, Extracellular, Srgn and IDBG-157635 and ENSMUSG00000020077 and 19073, BT.97928 and IDBG-629459 and ENSBTAG00000017863 and 509501

Gene info

• Identity
  HGNC:9361
• Gene
  SRGN
• Long gene name
  serglycin
• Synonyms gene
  • PRG
  • PRG1
• Synonyms gene name
  • proteoglycan 1, secretory granule
• Synonyms
  • PPG
• Synonyms name
  • serglycin proteoglycan
• GenBank acession
  • BC015516
• Locus
  10q22.1
• Discovery year
  1988-07-22
• Entrez gene record
  5552
• RefSeq identity
  • NM_002727
• Classification
  • Proteoglycans
• VEGA ID
  OTTHUMG00000018369

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products