Recombinant Human LIMP-2 / SCARB2 / CD36L2 Protein (His & Fc tag) 100µg
-
Catalog number
PKSH031285-100µg
-
Price
Please ask
-
Size
100µg
-
-
Synonym
AMRF;CD36L2;EPM4;HLGP85;LGP85;LIMP-2;LIMPII;SR-BII
-
Activity
Measured by its ability to bind recombinant human RSPO1 in a functional ELISA.
-
Sequence
Arg 27-Thr 432
-
Fusion tag
C-His & Fc
-
Accession
NP_005497.1
-
Expressed Host
HEK293 Cells
-
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
-
Purity
＞90 % as determined by SDS-PAGE
-
Endotoxin
＜1.0 EU per µg as determined by the LAL method
-
Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Mol Mass
74.4 kDa
-
AP Mol Mass
110-115 kDa
-
Formulation
Lyophilized from sterile PBS, pH 7.4
-
Reconstitution
Please refer to it for detailed information.
-
Background
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.
-
-
-
Conjugation
histidine
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
SCARB2, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2, RNU6-2, SNORD116-2
-
Short name
Recombinant LIMP-2 / SCARB2 / CD36L2 Protein (His & Fc tag) 100µg
-
Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
-
Label
His
-
Species
Human, Humans
-
Alternative name
Rec. H. sapiens LIMP-2 / scavenger receptor class B, member 2 / CD36L2 Protein (histidine & fragment c detection labelled) 100µg
-
Alternative technique
rec
-
Alternative to gene target
scavenger receptor class B, member 2, AMRF and CD36L2 and EPM4 and HLGP85 and LGP85 and LIMP-2 and LIMPII and SR-BII, SCARB2 and IDBG-25361 and ENSG00000138760 and 950, enzyme binding, Plasma membranes, Scarb2 and IDBG-180164 and ENSMUSG00000029426 and 12492, SCARB2 and IDBG-643116 and ENSBTAG00000010956 and 533177
-
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 7-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 329-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2005-07-11
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 512-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 521-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 1289-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 509-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2007-10-24
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
RNA, U6 small nuclear 2
-
Synonyms
-
Locus
-
Discovery year
2008-06-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
