Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His)

• Catalog number
  C356-500
• Price
  Please ask
• Size
  500 ug

• Description
  Recombinant Human TIM-3 is produced by our Mammalian expression system and the target gene encoding Ser22-Arg200 is expressed with a 6His tag at the C-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDEKFNLKLVIKPAKVTPAPTLQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLANELRDSRLANDLRDSGATIRVDHHHHHH
• Estimated molecular weight
  20,86 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  Q8TDQ0
• Other related products
• Additional description
  For cells, cell lines and tissues in culture till half confluency.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Immunoglobulin   Mucin   Domain-3/TIM3/HAVCR2   C-6His  
• Gene symbol
  HAVCR2
• Short name
  Recombinant T Immunoglobulin Mucin Domain-3/TIM3/HAVCR2 (C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Human TIM-3/HAVCR2(C-6His)
• Alternative technique
  rec
• Alternative to gene target
  hepatitis A virus cellular receptor 2, HAVCR2 and IDBG-55271 and ENSG00000135077 and 84868, protein binding, Plasma membranes, Havcr2 and IDBG-165782 and ENSMUSG00000020399 and 171285
• Tissue
  cell

Gene info

• Identity
  HGNC:18437
• Gene
  HAVCR2
• Long gene name
  hepatitis A virus cellular receptor 2
• Synonyms
  • Tim-3
  • TIM3
  • FLJ14428
  • TIMD3
  • CD366
• Synonyms name
  • T-cell immunoglobulin mucin family member 3
• GenBank acession
  • AK027334
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  84868
• Pubmed identfication
  • 11823861
• RefSeq identity
  • NM_032782
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000130249

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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