Rat Caspase 1 Protein (Recombinant)

Category

Proteins And Peptides
Clonality

N/A
Raised in

E. coli
Target

Rat Caspase 1 Protein
Immunogen

see included datasheet or contact us
Species reactivity

Human, Mouse, Rat (for other species please inquire)
Purification

Affinity purified
Applications

WB (for other applications please contact us)
Stock availability

Shipped within 5-12 working days.
Storage conditions

Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Footnote

This product is for research use only.
Other products
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Caspase Protein
Gene symbol

CASP9, CARD11, CASP2
Short name

Caspase 1 Protein (Recombinant)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Abbexa advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

Rat
Label

Unconjugated
Species

Rat, Rats
Alternative name

Rat caspase 1 Protein (Rec.)
Alternative technique

rec

Identity

HGNC:1511
Gene

CASP9
Long gene name

caspase 9
Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
Synonyms
- MCH6
- ICE-LAP6
- APAF-3
- PPP1R56
Synonyms name
- protein phosphatase 1, regulatory subunit 56
GenBank acession
- U60521
Locus

1p36.21
Discovery year

1996-11-11
Entrez gene record

842
Pubmed identfication
- 8663294
- 9390557
RefSeq identity
- NM_032996
Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
VEGA ID

OTTHUMG00000002256

Identity

HGNC:16393
Gene

CARD11
Long gene name

caspase recruitment domain family member 11
Synonyms gene name
- caspase recruitment domain family, member 11
Synonyms
- CARMA1
- BIMP3
Synonyms name
- card-maguk protein 1
- bcl10-interacting maguk protein 3
GenBank acession
- AF322641
Locus

7p22.2
Discovery year

2001-08-13
Entrez gene record

84433
Pubmed identfication
- 11278692
- 11356195
RefSeq identity
- NM_032415
Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- Caspase recruitment domain containing
- CBM complex
VEGA ID

OTTHUMG00000023023
Locus Specific Databases
- LRG_729

Identity

HGNC:1503
Gene

CASP2
Long gene name

caspase 2
Synonyms gene
- NEDD2
Synonyms gene name
- neural precursor cell expressed, developmentally down-regulated 2
- caspase 2, apoptosis-related cysteine peptidase
Synonyms
- ICH1
- PPP1R57
- MGC2181
Synonyms name
- protein phosphatase 1, regulatory subunit 57
GenBank acession
- AK096245
- BC002427
- BM998653
- BX537669
- CB988674
- U13021
Locus

7q34
Discovery year

1994-01-21
Entrez gene record

835
Pubmed identfication
- 7789948
- 8780721
- 19075813
RefSeq identity
- NM_032982
Classification
- Caspases
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
VEGA ID

OTTHUMG00000023641

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data