RAF265 for cell activation

RAF265 for cell activation is available 2 times from Biovision labs

2856-5 | RAF265 for cell activationsize: 5 mg | 219.05 USD

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2856-25 | RAF265 for cell activationsize: 25 mg | 692.49 USD

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  • Description
    RAF265 (CHIR-265) is a potent and selective inhibitor of C-Raf/B-Raf/B-Raf V600E (IC₅₀ of 3-60 nM); displays potent inhibition on VEGFR2 phosphorylation with EC₅₀ of 30 nM. RAF265 inhibits the growth of advanced human melanoma tumors.
  • Peptide sequence
    N/A
  • CAS number
    927880-90-8
  • Molecular weight
    518.41
  • Category
    Biochemicals
  • Other name
    1-Methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine; CHIR265
  • Molecular formula
    C₂₄H₁₆F₆N₆O
  • Physical appearance
    Light yellow to yellow solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>100 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    RAF265 for activation
  • Technique
    activation
  • Alternative name
    RAF265 to measure cellular activation
  • Tissue
    cell
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