Rabbit Anti-Lipopolysaccharides (LPS) from E. coli (K-235) antiserum
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Catalog number
LPS24-S
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Price
Please ask
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Size
100 ul
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Stock availability
Available
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Category
Primary Antibodies
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Antibody type
Polyclonal Antibody
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Antibody host
Rabbit
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Antibody conjugate
N/A
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Technical datasheet
Contact Gentaur to request the datasheet or ask our specialists for more information.
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Notes
The Rabbit Anti-Lipopolysaccharides (LPS) from E. coli (K-235) antiserum is manufactured for Research Use Only or for diagnostics purposes.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene
Bacterial pathogen lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans. LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A. The lipid A component is the primary immunostimulatory center of LPS. With respect to immunoactivation in mammalian systems, the classical group of strongly agonistic (highly endotoxin) forms of LPS has been shown to be comprised of a rather similar set of lipid A types. In addition, several natural or derivative lipid A structures have been identified that display comparatively low or even no immunostimulation for a given mammalian species. Some members of the latter more heterogeneous group are capable of antagonizing the effects of strongly stimulatory LPS/lipid A forms. Agonistic forms of LPS or lipid A trigger numerous physiological immunostimulatory effects in mammalian organisms, but--in higher doses--can also lead to pathological reactions such as the induction of septic shock. Cells of the myeloid lineage have been shown to be the primary cellular sensors for LPS in the mammalian immune system. During the past decade, enormous progress has been obtained in the elucidation of the central LPS/lipid A recognition and signaling system in mammalian phagocytes. According to the current model, the specific cellular recognition of agonistic LPS/lipid A is initialized by the combined extracellular actions of LPS binding protein (LBP), the membrane-bound or soluble forms of CD14 and the newly identified Toll-like receptor 4 (TLR4)*MD-2 complex, leading to the rapid activation of an intracellular signaling network that is highly homologous to the signaling systems of IL-1 and IL-18. The elucidation of structure-activity correlations in LPS and lipid A has not only contributed to a molecular understanding of both immunostimulatory and toxic septic processes, but has also re-animated the development of new pharmacological and immuno-stimulatory strategies for the prevention and therapy of infectious and malignant diseases.
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About
Rabbits are used for polyclonal antibody production by adi. Rabbit antibodies are very stable and can be stored for several days at room temperature. adi adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
H4C13, IRF6, TUBA1B, RAP2A, GPC4, CPAMD8, H2BC10, KRAS
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Short name
Rabbit Anti-Lipopolysaccharides (LPS) from (K-235) antiserum
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Technique
Rabbit, anti-, anti, antibody to, antibodies
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Host
Rabbit, Escherichia coli, Recombination of bioactive proteins and longer peptides in Escherichia Coli is done often with His tagging. adi supplies Rec. E. Coli affinity purified or tag purified antigens in 1 quantities or bulk volumes on request. Rabbits
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Species
Custom Service, E. coli
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Alternative name
production species: rabbit Antibody toLipopolysaccharides (LPS) from E. coli (K-235) antibodies
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Alternative technique
rabbit-anti, antibodies, escherichia
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Gene info
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Identity
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Gene
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Long gene name
H4 clustered histone 13
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Synonyms gene
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Synonyms gene name
- H4 histone family, member K
- histone 1, H4l
- histone cluster 1, H4l
- histone cluster 1 H4 family member l
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
tubulin alpha 1b
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
glypican 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1996-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 10
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Synonyms gene
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Synonyms gene name
- H2B histone family, member K
- histone 1, H2bi
- histone cluster 1, H2bi
- histone cluster 1 H2B family member i
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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