Rabbit Anti-Human MAPK12 Polyclonal: Unconjugated
-
Catalog numberSPC-1182D
-
PricePlease ask
-
Size100 µl
-
-
ImmunogenSynthetic peptide of human MAPK12 (AA323-337)
-
Antibody s targetHuman MAPK12
-
Antibody s full descriptionRabbit Anti-Human MAPK12 Polyclonal
-
Antibody s categoryPolyclonal Antibodies
-
Antibody s other nameERK 3 antibody, ERK 5 antibody, ERK 6 antibody, Extracellular signal-regulated kinase 6 antibody, MAP kinase 12 antibody, MAP kinase p38 gamma antibody, MAPK 12 antibody, Mapk12 antibody, Mitogen Activated Protein Kinase 12 antibody, Mitogen activated protein kinase 3 antibody, Mitogen activated protein kinase p38 gamma antibody, Mitogen-activated protein kinase 12 antibody, Mitogen-activated protein kinase p38 gamma antibody, MK12_HUMAN antibody, P38GAMMA antibody, PRKM12 antibody, SAPK3 antibody, Stress Activated Protein Kinase 3 antibody
-
Verified applicationsWB, AM
-
Raised inRabbit
-
Antibody s reactivityHuman, Mouse
-
Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
-
Antibody s purified fromPeptide Affinity Purified
-
Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
-
Antibody s concentrationSee included datasheet or contact our support service
-
Antibody s specificityDetects 41.94 kDa.
-
Storage recommendations-20°C
-
Shipping recommendationsBlue Ice or 4°C
-
Certificate of analysisA 1:250 dilution of SPC-1182 was sufficient for detection of MAPK12 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
-
Antibody in cellCytoplasm, Mitochondrion
-
Tissue specificityHighly expressed in skeletal muscle and heart.
-
Scientific contextMAPK12 is a protein-serine/threonine kinase. Part of the p38 stress pathway which prevents cell cycle progression. Many cancer cells will upregulate MAPK12 activity to kill cancer cells. Loss of function may be important to confer survival and inhibit apoptosis for tumour cells.
-
BibliographyRefer to PubMed
-
Released date29/Aug/2016
-
NCBI numberNP_002960
-
Gene number6300
-
Protein numberP53778
-
PubMed numberRefer to PubMed
-
Tested applicationsTo be tested
-
Tested reactivityTo be tested
-
Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
-
Representative figure linkNo Data Available
-
Warning informationNon-hazardous
-
Country of productionCanada
-
Total weight kg1.4
-
Net weight g0.1
-
Stock availabilitIn Stock
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
TestStressMark antibodies supplies antibodies that are for research of human proteins.
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
Conjugationnot conjugated
-
Gene target
-
Gene symbolMAPK12
-
Short nameRabbit Anti- MAPK12 Polyclonal: Unconjugated
-
Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
HostRabbit, Rabbits
-
IsotypeImmunoglobulin
-
LabelUnconjugated
-
SpeciesHuman, Humans
-
Alternative nameproduction species: rabbit Antibody toHuman MAPK12 polyclonal: nonconjugated
-
Alternative techniquepolyclonals, rabbit-anti, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namemitogen-activated protein kinase 12
-
Synonyms gene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-04-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Mitogen-activated protein kinases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data