Rabbit anti Discoidin Domain Receptor (DDR1)

• Catalog number
  X2257P
• Price
  Please ask
• Size
  50 μg

• Category
  Primary Antibodies
• Long description
  May be involved in cell-cell interactions and recognition. Expressed at low levels in most adult tissues and is highest in the brain and lung. Abundant in breast carcinoma cell lines.
• Antibody come from
  internal domain of human phosphodiesterase 3A protein.
• Other description
  Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Discoidin Domain Receptor (DDR1) Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Immunohistochemistry
• Antibody s suited for
  Antibody can be used for immunohistorchemistry (10-20 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  Long term: -70ºC; Short term: +4ºC
• Relevant references
  1. Wechsler, J., et al. 'Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytes.' J. Biol. Chem. 2002, 277(41), 38072-38078_x000B__x000B_2. Han, S.J., et al. 'Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation.' EMBO J. 2006, 25(24), 5716-5725_x000B_
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Discoidin   Domain   Receptor   DDR1  
• Gene symbol
  DDR1-DT, DDR1
• Short name
  Rabbit anti Discoidin Domain Receptor (DDR1)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Discoidin Domain Receptor (discoidin domain receptor tyrosine kinase 1)
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  discoidin domain receptor tyrosine kinase 1, CAK and CD167 and DDR and EDDR1 and HGK2 and MCK10 and NEP and NTRK4 and PTK3 and PTK3A and RTK6 and TRKE, DDR1 and IDBG-76157 and ENSG00000204580 and 100616237,780, transferase activity, Extracellular, Ddr1 and IDBG-178873 and ENSMUSG00000003534 and 12305, DDR1 and IDBG-634478 and ENSBTAG00000010682 and 534092

Gene info

• Identity
  HGNC:28694
• Gene
  DDR1-DT
• Long gene name
  DDR1 divergent transcript
• Synonyms gene
  • TIGD1L
  • DDR1-AS1
• Synonyms gene name
  • tigger transposable element derived 1-like
  • DDR1 antisense RNA 1 (non-protein coding)
  • DDR1 antisense RNA 1
  • DDR1 antisense RNA 1 (head to head)
• Synonyms
  • bPG70P20.2
  • bCX111D4.7
  • bQB10J12.1
• GenBank acession
  • AL137624
• Locus
  6p21.33
• Discovery year
  2004-06-15
• Entrez gene record
  414771
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000031229

Gene info

• Identity
  HGNC:2730
• Gene
  DDR1
• Long gene name
  discoidin domain receptor tyrosine kinase 1
• Synonyms gene
  • NTRK4
  • PTK3A
  • NEP
  • CAK
  • EDDR1
• Synonyms gene name
  • discoidin domain receptor family, member 1
• Synonyms
  • RTK6
  • CD167
• GenBank acession
  • X99031
• Locus
  6p21.33
• Discovery year
  1994-08-29
• Entrez gene record
  780
• Pubmed identfication
  • 7789998
• RefSeq identity
  • NM_013994
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000031236

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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