Rabbit anti Ah Receptor (AHR)
-
Catalog number
X2250P
-
Price
Please ask
-
Size
50 μg
-
-
Category
Primary Antibodies
-
Long description
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.
-
Antibody come from
internal domain of human
-
Other description
Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
-
Clone
Polyclonal
-
Antigen antibody binding interaction
Rabbit anti Ah Receptor (AHR) Antibody
-
Antibody is raised in
Rabbit
-
Antibody s reacts with
Human
-
Antibody s reacts with these species
This antibody doesn't cross react with other species
-
Antibody s specificity
No Data Available
-
Application
Immunohistochemistry
-
Antibody s suited for
Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (15-30 µg/ml). Optimal concentration should be evaluated by serial dilutions.
-
Storage
Long term: -70ºC; Short term: +4ºC
-
Relevant references
no information yet
-
Protein number
see ncbi
-
Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin name
Oryctolagus cuniculus
-
Gene target
-
Gene symbol
AHR
-
Short name
Rabbit anti Ah Receptor (AHR)
-
Technique
Rabbit, anti, antibody to
-
Host
Rabbit, Rabbits
-
Isotype
not specified
-
Label
unlabeled
-
Alternative name
production species: rabbit antibody to Ah Receptor (aryl hydrocarbon receptor)
-
Alternative technique
rabbit-anti, antibodies
-
Alternative to gene target
aryl hydrocarbon receptor, bHLHe76, AHR and IDBG-8995 and ENSG00000106546 and 196, E-box binding, nuclei, Ahr and IDBG-134957 and ENSMUSG00000019256 and 11622, AHR and IDBG-629848 and ENSBTAG00000007746 and 280714
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
