PTPN13 (T32-7G5) Monoclonal Antibody
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Catalog number
bsm-50422M
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Price
Please ask
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Size
0.1ml
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Long name
PTPN13 (T32-7G5) Monoclonal Antibody
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Also known as
PTPN13 (T32-7G5) Monoclonal Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
PTPN13
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Specificity
This is a highly specific antibody against PTPN13.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Monoclonal
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Clone number
T32-7G5
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Source
Recombinant human protein purified from E.coli
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Swiss Prot
Q12923
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Tested Applications
WB
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Recommended dilutions
WB (1:2000)
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Cross reactivity
Human
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene.[1][2] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.[2] PTPN13 has been shown to interact with PKN2.[3]
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Purification method
Ammonium sulfate precipitation
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps
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Gene target
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Gene symbol
PTPN13
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Short name
Anti-PTPN13
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Technique
Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Host
Mouse (Mus musculus)
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Isotype
Immunoglobulin G (IgG)2b
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Alternative name
PTPN13 (T32-7G5) Monoclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase), FAP-1 and hPTP1E and PNP1 and PTP-BAS and PTP-BL and PTP1E and PTPL1 and PTPLE, PTPN13 and IDBG-28517 and ENSG00000163629 and 5783, phosphatase activity, nuclei, Ptpn13 and IDBG-184669 and ENSMUSG00000034573 and 19249, BT.64781 and IDBG-643280 and ENSBTAG00000014947 and 282333
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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