Phospholipase C beta 3 Antibody
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Catalog number
bs-4702R
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Price
Please ask
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Size
0.1ml
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Long name
Phospholipase C beta 3 Antibody
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Also known as
Phospholipase C beta 3 Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
Phospholipase C beta 3
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Specificity
This is a highly specific antibody against Phospholipase C beta 3.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PLC beta3
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
PLCB3; PLC beta3;1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3;1-phosphatidylinositol-4;5-bisphosphate phosphodiesterase beta-3;Phosphoinositide phospholipase C;Phosphoinositide phospholipase C-beta-3;Phospholipase C beta 3;Phospholipase C beta 3 phosphatidylinositol specic;Phospholipase C-beta-3;PLC beta 3;PLC-beta-3;Plcb3;PLCB3_HUMAN.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PLCB3
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Short name
Anti-Phospholipase C beta 3
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
Phospholipase C beta 3 Antibody
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
phospholipase C beta 3
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Synonyms gene name
- phospholipase C, beta 3 (phosphatidylinositol-specific)
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GenBank acession
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Locus
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Discovery year
1994-11-17
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
- C2 domain containing phospholipases
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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