PF-431396

• Catalog number
  2844-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-Methyl-N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide
• Description
  PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor with IC₅₀ values 2 and 11 nM respectively.
• CAS Number
  717906-29-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₁F₃N₆O₃S
• Molecular Weight
  506.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD21608515
• PubChem CID
  11598628
• PubChem CID Link
• SMILES
  CN(C1=CC=CC=C1CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
• InChi
  InChI=1S/C22H21F3N6O3S/c1-31(35(2,33)34)18-6-4-3-5-13(18)11-26-20-16(22(23,24)25)12-27-21(30-20)28-15-7-8-17-14(9-15)10-19(32)29-17/h3-9,12H,10-11H2,1-2H3,(H,29,32)(H2,26,27,28,30)
• InChi Key
  POJZIZBONPAWIV-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PF-431396  
• Short name
  PF-431396
• Alternative name
  PF-431396

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