PF 04554878 for cell activation

PF 04554878 for cell activation is available 0 time from Biovision labs

  • Description
    PF-04554878 is potent, ATP-competitive, focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. PF-04554878 inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.  A combination of PF-04554878 and paclitaxel markedly decreases proliferation and increases apoptosis.
  • Peptide sequence
    N/A
  • CAS number
    1073154-85-4
  • Molecular weight
    510.49
  • Category
    Biochemicals
  • Other name
    N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide; Defactinib; VS-6063
  • Molecular formula
    C₂₀H₂₁F₃N₈O₃S
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (~40 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    PF-04554878 for activation
  • Technique
    activation
  • Alternative name
    PF-04554878 to measure cellular activation
  • Tissue
    cell
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