PF-04447943

• Catalog number
  B1264-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-[2-(diethylamino)ethyl]-2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1H-Cyclopentapyrimidine-1-acetamide; SB-480848
• Description
  PF-04447943 is a potent, brain-penetrant and selective inhibitor of PDE9 (Phosphodiesterase 9) (Ki of 2.8, 4.5 and 18 nM for human, rhesus and rat recombinant PDE9 respectively). Displays high selectivity for PDE9 versus PDEs1-8 and 10-11.
• CAS Number
  1082744-20-4
• Structure Available
  Yes
• Molecular Formula
  C₂₀H₂₅N₇O₂
• Molecular Weight
  395.46
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, brain-penetrant and selective PDE9 (Phosphodiesterase 9) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  25115162
• PubChem CID Link
• SMILES
  CC1CN(CC1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5
• InChi
  InChI=1S/C20H25N7O2/c1-13-10-26(12-17-21-5-2-6-22-17)11-16(13)18-24-19-15(20(28)25-18)9-23-27(19)14-3-7-29-8-4-14/h2,5-6,9,13-14,16,23H,3-4,7-8,10-12H2,1H3/t13-,16-/m1/s1
• InChi Key
  ACXPOEVOYNJCHF-CZUORRHYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PF-04447943  
• Short name
  PF-04447943
• Alternative name
  PF-04447943

Similar products